in 2009:"For a lot of people, Gleevec was simply too good to be true. But these once-dying patients were getting out of bed, dancing, going hiking, doing yoga. The drug was amazing.” Phase I clinical trials are largely to establish the safety profile of brand new drugs that have only previously been tested in animal models. However, remarkably, 98% of the patients on this initial trial were still alive five years after treatment and some of them are still alive today.
Carrasco will almost certainly be on Imatinib, or one of the similar variants of the drug developed since the original FDA-approval in 2001 to treat his CML. Importantly for his athletic career, because the drugs are specific for the CML cells, in most people they come with minimal side-effects, especially when compared with conventional chemotherapies that are often used for other types of leukemia that do not have the Philadelphia chromosome.
Although coming with undoubtedly fewer side-effects than many cancer drugs, Imatinib and its variants are not flawless. Itome problems, especially when taken long-term as is the norm with most people with CML, but the majority of people taking it do well and experience minimal to no issues. If Carrasco is one of these people, he should be able to hopefully continue his MLB career unimpeded.I am a postdoctoral research scientist focusing on childhood cancers and new, targeted cancer therapies.
Short answer: Some cancers are chronic and treatable. You can live with them for decades. T+1504
Money 💰 usually decides unfortunately
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