Not plaque but a protein is the keyThe researchers of the new study examined the concentration of amyloid plaques and the amyloid-beta protein in two groups. The first group included people that had very high chances ofaccording to the 2006 study. The researcher spotted mutations in their bodies which indicated the development of amyloid plaques in the future.
The second group involved healthy individuals. In both cases, the researchers noticed that individuals with low concentrations of soluble amyloid-beta protein were at greater risk of suffering from dementia. Whereas others that were more likely to have amyloid plaques in their brains in the future but had high concentrations of the proteinProfessor of Clinical Division Director at UC College of Medicine and one of the authors of the study, Alberto J.
, “What we found was that individuals already accumulating plaques in their brains who are able to generate high levels of soluble amyloid-beta have a lower risk of evolving into dementia over a three-year span.”The concentration of soluble amyloid-beta protein decreases when it turns into insoluble amyloid plaques due to various stress factor that affects its metabolism.
Source: Healthcare Press (healthcarepress.net)
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