USC vs Colorado Predictions - NCAAF Week 5 Betting Odds, Spreads & Picks 2023

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College football odds, picks and prediction for USC Trojans vs Colorado Buffaloes. Week 5 betting free pick and game analysis.

Coach Prime and the Colorado Buffs got housed by Oregon in Week 4 and won't have it much easier this weekend against Caleb Williams and the USC Trojans. We break down the best bet and more in our USC vs. Colorado betting preview below.Coming off their first loss of the season, Coach Prime and the Colorado Buffaloes return home to the confines of Boulder.

It should come as no surprise that the Trojans have been elite on offense again this season. They lead the nation with 55 points per game and yards per play and rank third with 569.3 total yards per game. There’s no other way to say it — this is about as good of an offense as you'll see at the college level.

Leading receiver Xavier Weaver is considered questionable after getting banged up and exiting last week’s game late. Travis Hunter is still expected to be on the shelf, leaving the Buffs without one of its top receivers and its top cornerback in one fell swoop.

 

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