The region is a major global supplier of cotton, so the order could have significant effects on global commerce.
The Trump administration has already blocked imports from individual companies linked to alleged forced labour in the region. Some manufacturers have criticised the use of a region-wide order, arguing it can be hard to ensure tainted raw materials do not enter the supply chain. That is especially true with Chinese cotton that is used to make clothing for export in other countries such as Bangladesh and Vietnam.
Customs and Border Protection has in the past targeted entire product lines and regions with import bans, including issuing an order against cotton from Turkmenistan in 2018 and gold from artisanal mines in eastern Democratic Republic of the Congo in 2019.
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