Unlocking Nature’s Disappearing Act: Human Cells Decipher the Secrets of Squid Camouflage

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Human Cells Help Researchers Understand Squid Camouflage Squids and octopuses are masters of camouflage, blending into their environment to evade predators or surprise prey. Some aspects of how these cephalopods become reversibly transparent are still “unclear,” largely because researchers can’t cu

Researchers have replicated the tunable transparency of squid skin cells in mammalian cells, which can be cultured, potentially leading to better cell imaging techniques. The team at the University of California, Irvine, focused on cephalopod cells called leucophores and introduced squid-derived genes encoding reflectin proteins into human cells. By adding salt to the cells’ culture media, they observed reflectin proteins forming nanostructures that altered the cells’ opacity.

By incorporating squid proteins in mammalian cells, researchers could tune the cells’ transparency from clear to cloudy . Credit: Adapted from ACS Biomaterials Science & Engineering, 2023, DOI: 10.1021/acsbiomaterials.2c00088 To change how light interacts with cultured cells, Georgii Bogdanov, a graduate student in Gorodetsky’s lab who is presenting the results, introduced squid-derived genes that encoded for reflectin into human cells, which then used theto produce the protein.

 

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