Widely distributing boosters is "not appropriate," the authors, including two senior FDA officials and multiple scientists from the World Health Organization, wrote.
Fully vaccinated people without underlying conditions are another story, particularly if they received an mRNA vaccine. People with "adequate" immune responses — meaning the vaccines successfully help prevent severe illness, hospitalization and death — probably don't need a third dose right now, Khan says.
Booster timelines are currently determined using available metrics like antibody levels and other lab markers, Kahn says, adding that more research is needed to figure out exactly what the optimal time range would be to administer the shots.
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