The New Clues About Who Will Develop Long Covid

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Scientists are gaining a better understanding about why some people get long Covid and others don’t

. Patients with autoantibodies, for instance, might get relief from existing treatments for lupus, an autoimmune disease.

Most patients didn’t have a diagnosed autoimmune disease, but rather had very low levels of autoantibodies associated with various autoimmune diseases, says Jim Heath, senior author on the study and president and professor of the Institute for Systems Biology, a nonprofit biomedical research organization in Seattle.. Epstein-Barr is what causes mononucleosis and infects about 90% of people. Normally, the virus remains dormant afterward.

Two other risk factors were Type 2 diabetes and the detection of genetic material from SARS-CoV-2 in the blood, which means the virus escaped the lungs and is spreading to other parts of the body. The researchers also found that some long Covid patients have very depleted levels of the cortisol hormone, resulting in Addison’s disease, which has symptoms such as fatigue and muscle aches. Addison’s patients are often treated with cortisol replacement therapy.

 

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