The days of cancer relapse are over, thanks to this novel chemoimmunotherapy

Professor Li and his team figured out that to prevent the recurrence of cancer, they need to stop PS from migrating to the cell surface. They dug deep and discovered that the accumulation of PS on the tumor cell surface is actually controlled by a protein called Xkr8. Interestingly, another

The surface of the nanoparticles was loaded with chondroitin sulfate and polyethylene glycol to ensure their safe and easy delivery to the. These chemicals allow the nanoparticles to ignore healthy cells and only bind with cell receptors on cancerous blood vessels and tissues. Moreover, CS and PEG also enabled a significant number of nanoparticles to reach the targeted tumor cells.

The researchers observed two groups of mice; the first group underwent chemoimmunotherapy , and the second group was treated with conventional chemotherapy that involved the use of only FuOXP. Movement of PS from the membrane to the tumor cell surface was found to be reduced to a large extent in mice belonging to the first group.

PD-1 is an abbreviation for "programmed cell death protein 1," which is considered a checkpoint molecule. It serves as a brake and limits the magnitude of the immunecells. So when the PD-1 expression level is high, it limits the magnitude of the anti-tumor immune response.

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