Last year, the TRAVERSE trial was the first randomized, placebo-controlled study designed and powered to determine whether testosterone therapy increased risk for major cardiovascular events in men . Its conclusionsBut other studies have had different conclusions and TRAVERSE left unanswered questions, so Bu B.
The link between higher SHBG concentrations and higher all-cause mortality"may be related to its role as the major binding protein for sex steroids in the circulation," the authors wrote."We found a U-shaped association of DHT with all-cause and CVD-related mortality risks, which were higher at lower and very high DHT concentrations. Men with very low DHT concentrations also had increased risk for incident CVD events.
The main finding from the Yeap et al. study, he wrote, is that high testosterone concentrations at baseline were not linked with increased deaths from CVD or from all causes"but very low serum total testosterone concentrations at baseline were.
Cardiovascular Risk CV Risk Factors Cardiovascular Risk Factors Cardiovascular Risk Management Hypogonadism Testosterone Low Testosterone Low T Testosterone Therapy Steroids Stroke Cerebrovascular Accident CVA - Cerebrovascular Accident Myocardial Infarction Patient Safety Meta-Analysis Mass Spectrometry Adverse Effects Side Effects Aromatase Inhibitor Exemestane Bones Infarct
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