'Synthetic' Embryo Grown by Cambridge Scientists

Researchers from the University of Cambridge have used mouse stem cells to create a model embryo in the laboratory – a breakthrough they describe as "a new avenue for recreating the first stages of life".

"It’s just unbelievable that we’ve got this far. This has been the dream of our community for years, and the major focus of our work for a decade, and finally we’ve done it," she said. Eventually the stem cells self-organised into structures that progressed through successive developmental stages until they had assembled into embryo models that displayed head-folds with defined forebrain and midbrain regions, and developed a beating heart-like structure, a trunk comprising a neural tube and somites, a tail bud containing neuromesodermal progenitors, a gut tube, and primordial germ cells.

"This period of human life is so mysterious, so to be able to see how it happens in a dish – to have access to these individual stem cells, to understand why so many pregnancies fail and how we might be able to prevent that from happening – is quite special," she said. "We looked at the dialogue that has to happen between the different types of stem cell at that time – we’ve shown how it occurs and how it can go wrong.

Source: Education Headlines (educationheadlines.net)

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