Gene-edited pigs are moving closer to supplying kidneys and livers that humans can tolerate. Two newly reported transplants of genetically modified pig organs into humans mark firsts in a long-struggling field that hopes to use xenotransplantation to help people who have failed livers or kidneys. At Massachusetts General Hospital,reported today.
The second transplant took place in China at Xijing Hospital of the Air Force Military Medical University. Here,reported, the patient was “clinically dead” because of brain damage and had the organ removed after 10 days. The team saw no signs of immune rejection, and the liver produced bile as hoped. The pig had three pig genes disabled and three human ones added to prevent immune rejection.
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