Imbalance s in microbial populations have previously been observed in stool samples of patients with obesity-related diseases. This is the first study to fully examine the small bowel microbiome in different weight categories.
Duodenal aspirates and serum samples were obtained from 214 adults undergoing routine esophagogastroduodenoscopy without colon preparation.IN PRACTICE: "We identify small bowel microbial species associated with overweight and obesity, as well as escalation and de-escalation features that could potentially be selected as therapeutic targets. These findings illustrate that, although stool studies can and have provided very valuable data, direct analysis of the small bowel has yielded specific targets for further study," the authors wrote.
Obese Duodenal Dyslipidemia Dyslipidaemia Metabolism Metabolic Small Intestinal Microbiome Microbiota Biomarker Biological Marker Multi-Biomarker Disease Activity MBDA Multibiomarker Disease Activity Blood Diet Endoscopy Escherichia Coli Escherichia Coli Infection E. Coli E. Coli Infection Esophagogastroduodenoscopy Imbalance Lipids Lipid Management
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