Music at a blaring concert, racket from tools at a construction site, or the firing of weapons can all cause noise-induced hearing loss. An acute traumatic injury to the ear from loud sounds can even progress into some more severe conditions including tinnitus and hyperacusis. People with tinnitus hear ringing or buzzing that isn’t there, while those with hyperacusis generally experience normal levels of sound as painful. “Noise-induced hearing loss is very common and debilitating.
“As previous literature showed, dysregulation in zinc signaling can cause cell degeneration and death and contributes to conditions like ischemia and optic nerve degeneration,” says Tzounopoulos. A zinc trap In the study, the team used mice to explore if zinc dysregulation plays a role in the damage that loud noises can do to the inner ear. Only a few hours after the mice were exposed to loud sounds, a robust release of zinc into the space between cells occurred.
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