Scientists Have Discovered a New Cause of Parkinson’s Disease

A major discovery sheds light on the underlying mechanisms of Parkinson’s disease, opening the door for novel therapeutic approaches down the line.

“For the first time, we can show that mitochondria, the vital energy producers within brain cells, particularly neurons, undergo damage, leading to disruptions in mitochondrial. This initiates and spreads the disease like a wildfire through the brain,” says Shohreh Issazadeh-Navikas and adds: The disease afflicts over 10 million people worldwide. While there is currently no cure, certain medical treatments can offer relief from its symptoms.By examining both human and mouse brains, researchers discovered that the damage to mitochondria in brain cells occurs and spreads when these cells have defects in anti-viral response genes. They sought to understand why this damage occurred and how it contributed to the disease.

Biomarkers are objective indicators of specific medical conditions observed in patients. While some biomarkers are common, such as blood pressure, body temperature and body mass index, others provide insights into particular diseases, like gene mutations in cancer or level of blood sugar for diabetes. Identifying a biomarker for Parkinson’s disease holds significant promise for enhancing future treatments.

Source: Healthcare Press (healthcarepress.net)

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