Scientists Confirm That Stress Can Indeed Turn Hair Grey

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The cells that are targeted by the sympathetic nervous system under stress are a group of color-generating stem cells found deep in the so-called bulge of the hair follicle from which all new hair grows. Called melanocyte stem cells, these cells become active when a new hair begins to sprout in the follicle; the melanocyte stem cell then starts to divide and produce pigment-producing cells that color the shaft of the hair as it grows.

Hsu found that even during normal stress , the sympathetic nervous system is active, and produces the chemical norepinephrine, which leads to increased muscle contraction, including in the heart. In response to the norepinephrine, the melanocyte stem cells start churning out more than the usual allotment of pigment, misreading the stress-induced cue for the one that signals new hair growth. Eventually, their color reservoir runs dry and they can’t produce pigment any more.

The connection between stress and the nervous system and pigment-producing cells may be an evolutionarily conserved association among different species—cephalopods, including squid and octopi, also change color when under stress. Whether something similar is at work in mammals and greying hair isn’t clear yet, but these findings are a reminder that stress has widespread effects on the body, and may be working in ways that doctors still don’t fully understand.

Based on these findings, it’s possible that there may eventually be a way to either preserve the melanocyte stem cells, or control the effect that the sympathetic nervous system has on their number. But for now, Hsu says, “There is no treatment available at this very moment. There is still a lot of work to do in this area.”

Good to see science catching up with what chinesemedicine has known for centuries

Known that since childhood nothing new

🤦‍♂️

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