Row breaks out over WHO trial casting doubt on remdesivir as COVID-19 drug

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A row broke out on Friday over a World Health Organization (WHO) clinical trial which concluded that the anti-viral drug remdesivir has little or no impact on a patient's chances of surviving COVID-19.

ZURICH/GENEVA - A row broke out on Friday over a World Health Organization clinical trial which concluded that the anti-viral drug remdesivir has little or no impact on a patient’s chances of surviving COVID-19.

But Richard Peto, an independent statistician hired by the WHO to scrutinize the results of its Solidarity trial, dismissed Gilead’s criticism. Its trial was conducted on 11,266 adult patients in over 30 countries and its findings may shift the focus of treatments away from antivirals such as remdesivir to new monoclonal antibodies which the WHO has said could be added to its studies.

For the remdesivir arm of the WHO’s Solidarity trial, 2,743 patients were given remdesivir, compared to 2,708 in the control group. Gilead’s study had 1,062 participants.

 

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