Princess Catherine is one of many more young adults with cancer

Britain’s Queen Elizabeth II, right, and Catherine, Duchess of Cambridge watch a fashion show at De Montfort University in Leicester, England, Thursday March 8, 2012.

But the 2024 report was different. Colorectal cancer moved as of 2021 to the leading cause of cancer death in men under 50, the report said, and second for women. Young adult oral and liver cancer deaths were increasing, along with deadly cervical tumors in women ages 30 through 44, reversing “decades of decline.”

Among the red flags: Deaths from colorectal cancer rose 17% among those 15 to 44 in that time, four times the population-wide increase. Uterine cancer deaths rose 37% among 25-to-44-year-olds from 2019 to 2023; they rose 15% overall. “Colorectal cancers are also presenting with more aggressive disease and larger tumors at diagnosis,” said William Dahut, the American Cancer Society’s chief scientific officer, after the report’s release. “It’s more difficult to treat,” he told NBC News.

Slowly but surely, researchers are documenting this tragic development in adolescents and young adults. A new preprint study of U.S. data found cancer deaths among 15-to-44-year-olds “accelerated substantially” in 2021, with an excess of nearly 6% above expected. That figure rose to 8% in 2022. A second study from the United Kingdom found “highly statistically significant” increases in cancer mortality in the same age group in 2021 and 2022.

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