Pregnancy complications linked to increased risk of early death even decades later, study finds

The study, published Monday in the journal JAMA Internal Medicine, found that women who experienced major complications during pregnancy had an increased risk of early death and that risk remained elevated for more than 40 years. “Adverse pregnancy outcomes may lead to small physiologic changes that are initially hard to detect, such as inflammation or other abnormalities in small blood vessels.

“It was striking that all five major adverse pregnancy outcomes were linked with increased mortality risks even more than 40 years after delivery,” Crump said in the email. “We found that the increased mortality was attributable to multiple different causes of death, including heart disease, diabetes, respiratory disorders, and cancer,” he said. “This suggests that there are multiple different underlying pathways that will need additional research to further identify.

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