Pills to treat COVID-19 will be game-changers, but the best strategy remains prevention

Nearly two years into the pandemic, it has become starkly clear that we need better treatments for COVID-19 for people in the earlier stages of disease.

As an infectious diseases physician and scientist at the University of Virginia, I have helped care for hundreds of people with COVID-19. I’ve also helped conduct clinical trials to find new treatments. Molnupiravir and Paxlovid would fill a need that hasn’t been met by other COVID-19 drugs, which are either difficult to administer or only suitable for patients in the hospital.

Early data suggests that both molnupiravir and Paxlovid are effective new drugs that patients can take at home to prevent complications of COVID-19 – which could be particularly beneficial for those at high risk of severe disease. Once authorized, these pills will allow patients to be treated earlier in the course of infection, at the point when antiviral drugs are more effective.

Molnupiravir and Paxlovid were studied in separate clinical trials with similar designs. In both studies, the drugs were tested in outpatients with risk factors for severe COVID-19 who were at an early stage in their illness. Both studies also looked at how likely patients were to either die or be hospitalized. However, neither study has yet been peer-reviewed.

If and when these drugs get authorized in the U.S., they will probably be used for the same higher-risk patients who are eligible for monoclonal antibodies today. Monoclonal antibodies may still be used, though, for pregnant people, people on dialysis and some immune-compromised patients.

Source: Healthcare Press (healthcarepress.net)

And if they look less like a nuclear hot dog

I don’t agree at all. The symptoms are pretty clear, high fever and loss of taste or smell. Have 24-48 hours and can take steroid inhalers or saline sprays. Don’t forget that an aspirin reduces chance of infection by 50%. Vit D really helps as well. Others but test good

ah look they have a pill for the common cold

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