Paxlovid Rebound in COVID-19: Where We Stand on Drug Regimens

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.DrRobertGlatter and PaulPauwaert discuss Paxlovid rebound and recommendations for patients with COVID-19. MedTwitter

, and we're talking about whether this is immune related. Is it circulating virus? Is it some other type of mechanism we're just not aware of at this point?I think the jury's out. Clearly, we know, for example, in myself, where I'm not taking any medication, there is. I didn't have any symptoms. I just had viral carriage. I had continued improvement during that time.

Now, with BA.5, especially, varying enough, there's enough immune escape that maybe the body hasn't enough chance to really adapt so by the time you withdraw the drug, there's not enough to keep the virus at bay. Those are just some of the ideas, and it may be multifactorial components. Another issue that I've seen is that maybe someone developed a secondary bacterial infection, such as sinusitis,

 

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