Opinion | The Attack on an Alzheimer’s Drug

new drug for Alzheimer’s. So now they’re mounting an assault on the drug’s cost to stop Medicare from paying for it. Their sudden and rare concern for the federal fisc is illuminating, and not in a good way.

Nobody has said Aduhelm is a cure, but it is the first treatment following hundreds of failures that has shown evidence in clinical trials of removing amyloid plaque—a hallmark of the disease—and slowing cognitive decline. Biogen learned from these failures, and the FDA noted that Aduhelm was the first drug to show “proof of concept” in an early stage trial that clearing amyloid could slow decline. This was supported by a Phase 3 trial in which patients receiving the highest dosage showed 25% to 28% less decline in memory and problem-solving compared to the placebo group after 78 weeks.

The FDA approved Aduhelm because it significantly reduced amyloid. Many of Aduhelm’s critics in the public-health crowd have criticized the FDA’s accelerated approval program for years. They don’t believe drugs with incremental benefits should be approved.

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opinion There is so much information out there about this drug not working....who’s paying you to say this? Disgusting.

opinion Laetrile ! Laetrile! Laetrile! A sucker IS born every minute. “ Do no harm “, is replaced by make money no matter who you kill .

opinion Why is it that the title isn’t: The price is much lower in other countries, price gouging is out of Control in the US!

opinion This is disingenuous. The drug, Aduhelm failed to show evidence of even “slowing” the progression of Alzheimer’s. The drug company initially abandoned the trial but later re-examined the data and “found” that in a small sub-sample, there was statistically significant result.

opinion C’mon. $56,000/patient/year? Outrageous.

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How a single new Alzheimer’s drug could blow up the federal budgetA single new Alzheimer's drug has the potential to explode the federal budget and move an already simmering debate over drug prices in Congress and the White House onto the front burner. 🤦‍♂️🤦‍♂️🤦‍♂️ 🤦‍♂️🤦‍♂️🤦‍♂️ samgandy Thank you the great article, but Aduhelm is not an 'Alzheimer's drug.' Should be, and many people think it is, given FDA approval, but it just isn't.
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