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Notre Dame vs. Duke picks, predictions: Week 5 college football odds, spread, lines

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Not many analysts thought this weekend’s game in Durham would feature two ranked teams, but it will be a No. 17 ranked Duke that square off against No. 11 Notre Dame in college football’s Week 5 action on Saturday. Duke took down a then-9th ranked Clemson in the season opener and responded with ...

in the season opener and responded with impressive showings in the next three games to sit at 4-1 on the year behind a balanced offensive attack led by quarterback Riley Leonard, a 68 percent passer with 6 all-purpose touchdowns and no turnovers, aided by a backfield churning out over 200 yards per game on the ground.despite Sam Hartman leading two statement touchdown drives in that game, and faces a more narrow window as it looks to play into College Football Playoff contention.

What do the experts think of the matchup? Let's see how the College Football Power Index computer prediction model projects the game.Notre Dame odds: The computers project the Fighting Irish will defeat Duke with 69.4 percent likelihood, winning the game outright in 13,880 of the 20,000 simulations the model uses to pick winners.Conversely, the Blue Devils come out as the winner in the remaining 30.6 percent of simulations, or 6,120 of the 20,000 projections.Notre Dame comes into the game as 5.5 point favorites against Duke, according to the lines at SI Sportsbook, which set the total at 53.5 points.

 

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