A research team at Pitt led by Alexander Star, a chemistry professor in the Kenneth P. Dietrich School of Arts and Sciences, has developed a fentanyl sensor that is six orders of magnitude more sensitive than any electrochemical sensor for the drug reported in the past five years. The portable sensor can also tell the difference between fentanyl and other opioids.Fentanyl is a synthetic opioid and one of the main drivers in overdose deaths in the United States, Star said.
At the core of each of these sensors is a chip with carbon nanotubes attached. Each tube is like a tiny wire that's 100,000 times smaller than a human hair and great at conducting electricity. Attached to the nanotubes are gold nanoparticles, each about 43 nanometers tall. The result was a sensor that's more sensitive than any electrochemical fentanyl sensor reported in the past five years. Star's sensors detected fentanyl on the femtomolar scale. That's 10-15 moles per liter. The next closest sensor can detect on the nanomolar scale, which is 10-9 moles per liter.
In the future, he anticipates using this technique to develop a sensor array that can detect many kinds of drugs.
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