Moderna says its updated booster raises antibodies against omicron subvariants

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The company's data still don't answer key questions, including whether the updated booster provides stronger protection against infection.

The results are based on blood samples taken from 511 adults who got the updated booster, which targets BA.4 and BA.5, along with the original coronavirus strain, in a single shot.

In people who got the updated booster, neutralizing antibodies against BA.4 and BA.5 were about fivefold higher in those with a previous Covid infection and sixfold higher in those without a documented infection, the company said. The preliminary results are “helpful,” especially as new variants emerge, said Dr. Isaac Bogoch, an infectious disease specialist at the University of Toronto.

 

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