Milk from before antibiotic era were resistant to antibiotic tetracycline

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The researchers started with 50 samples collected from 1941 to 1947, and they found that the samples contained seven different Streptococcus species, including two subspecies of S. dysgalactiae.

Interestingly, the researchers found some of the samples were resistant to the antibiotic tetracycline and did not carry antibiotic resistance genes typically seen in today's antibiotic-resistant bacterial strains. Since these samples were collected prior to the antibiotic era, the results add to a growing body of literature showing that antibiotic resistance occurred naturally before humans discovered and began to use antibiotics.

"We believe that most of them came from Connecticut or perhaps from cases from the region, but we cannot say which parts," Risatti says."Most likely, this lab provided a testing service to locals, as this was mainly a pathology lab. Now it's more like a diagnostic lab, and we receive samples from all over the region, including New York and New Jersey."

"Antibiotic resistance is a very big area of research, and it has been for many years," says Risatti."We did not go any further with our analysis because we don't have the tools here, but we hope to bring this information to the public. I think it could be the jumpstart for somebody to study further."

"This is a good platform for undergraduate students to gain experience and publish their findings. I am surprised by how eager these young people are. I am glad we can provide the space to do these things." Genome analysis of Streptococcus spp. isolates from animals in pre-antibiotic era with respect to antibiotic susceptibility and virulence gene profilesResearchers have discovered 18 new species of Enterococcus type bacteria from soil samples collected from all corners of the globe, which may offer new clues to the origins of antibiotic-resistant ...

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