J&J’s Covid-19 Vaccine: How Does the One-Dose Shot Compare With Others? What You Need to Know

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Availability of Johnson & Johnson's Covid-19 vaccine in the U.S. will be limited at first. Here's what we know about the shot.

authorized for use in the U.S.

by federal health regulators. It is the third shot to be cleared after shots from Pfizer Inc. and its partner BioNTech SE and from Moderna Inc. And it is the first shot requiring just one dose, rather than two. Here’s what we know and don’t know:They all work well, health experts say. The Pfizer-BioNTech and Moderna shots were more than 94% effective in their late-stage trials, while J&J’s effectiveness was 66%. But the difference may be less than it seems.

Yet health experts say J&J’s vaccine is plenty effective. Importantly, it was 85% effective against severe Covid-19 at least 28 days after vaccination. That suggests the vaccine should help many people avoid the kinds of serious cases that result in hospitalizations.The first one you can, health authorities say. It is possible that individuals won’t have much of a choice because of limited supplies and the vaccination site might only offer one of the shots.

 

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