In a Medical First, Surgeons Transplant Genetically Modified Pig Heart Into a Human

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It was a desperate attempt to save the patient’s life, but doctors hope the technique could one day ease the organ shortage crisis.

University of Maryland Medicinefor signs of rejection or infection. Should all continue to go well, Bennett will be disconnected from a heart-lung bypass machine.

“We are proceeding cautiously, but we are also optimistic that this first-in-the-world surgery will provide an important new option for patients in the future.”it has set an important medical precedent. The operation shows that it’s possible for a genetically modified pig heart to take the place of, and function similarly to, a human heart, and not be rejected by the body . The experimental technique represents a potential solution for easing the organ shortage crisis.

Regenerative medicine company Revivicor provided the xenotransplantation lab with the genetically modified pig. Pigs get a lot of attention in xenotransplantation research due to their physiological similarities to humans and nonhuman primates. In October 2021, Revivicor provided a pig kidney forpatient’s life.

The use of animal parts to treat heart conditions is hardly new. Pig heart valves have been used for many years to replace valves in humans. And back in the 1980s, a baby diagnosed with a fatal heart condition was given a baboon’s heart. The patient, known as Baby Fae, died a month later after her body rejected

 

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