, for instance, have increased over the past 20 years, prompting efforts to improve diagnosis and treatment, especially in early stages of the disease.
Patients with DNA polymerase-epsilon–mutated tumors, indicating a more favorable prognosis, should not receive adjuvant radiotherapy.The current analysis included 153 women diagnosed with non-mismatch repair deficiency stage I endometrioid endometrial cancer and compared their documented adjuvant radiotherapy regimens to radiotherapy strategies informed by molecular classification.
More specifically, patients with no specific molecular profile who received no adjuvant radiotherapy were considered undertreated . Patients with p53-abnormal endometrial cancer who did not receive pelvic external beam radiotherapy were also considered undertreated .
Source: Healthcare Press (healthcarepress.net)
Endometrial Cancer Carcinoma Of The Endometrium Cancer Of The Endometrium Radiation Therapy Radiotherapy Radiation Oncology Genomics Genomic Medicine Cancer Malignant Neoplasia Carcinoma Malignant Neoplasm Clinical Guidelines Guidelines Tumor Prognosis
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