Autophagy may engulf non-specific cell components, or selectively remove damaged components or invasive bacteria and other pathogens.
Under certain conditions, autophagy can also induce programmed cell death . In short, autophagy is a part of a cellular process that maintains cell homeostasis by finding a balance between making and breaking cellular components.Autophagy forms a part of the metabolic process which helps cells convert food into a form of energy that cells can use to grow and divide. Metabolism balances between two opposing activities, anabolism, and catabolism.
During autophagy, a semicircular membrane known as phagophore forms and closes around some of the molecules and organelles in the cytoplasm and becomes what is known as an autophagosome.that break down the contents of the autophagosome. The resulting molecules are released back into the cytosol to be recycled and used in the metabolic process.
Some studies have detected autophagy in human cultured neutrophils after 24 hours. There are, however, no conclusive studies on humans that indicate an optimal period of fasting to achieve autophagy. However, do not attempt to fast to induce autophagy without discussing this method with your doctor.
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