, could revolutionize wide swathes of biology by fundamentally changing how protein structure is studied and leveraged for drug design. The study was led by Van Andel Institute's Juan Du, Ph.D., and Wei Lü, Ph.D.
Proteins are the molecular workhorses of the body. Their shape governs how they interact with other molecules to do their jobs. By determining protein structure, scientists can create blueprints that guide development of more effective medications, much like locksmiths designing keys to fit into specific locks.
To visualize TRPM4 at body temperature, the team leveraged VAI's powerful suite of cryo-electron microscopes , which allow scientists to flash freeze proteins and assemble detailed images of their structures. Rather than using a low-temperature sample, Postdoctoral Fellow Jinhong Hu, Ph.D., and colleagues in the Du and Lü laboratories heated the sample to body temperature before flash freezing it.
Obesity Pharmacology Cystic Fibrosis Molecular Biology Cell Biology Biotechnology Nature
We have summarized this news so that you can read it quickly. If you are interested in the news, you can read the full text here. Read more:
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Global Heating Will Cost The World Economy $38 Trillion — A Year!Global heating will cause upwards of $38 trillion in economic damage per year by mid-century according to a study from PIK.
Source: cleantechnica - 🏆 565. / 51 Read more »
Heating Up the Kitchen: Detroit-style pizza with Algonquin-Lake In the Hills Fire Protection DistrictThis morning we're Heating Up the Kitchen with the Algonquin-Lake In the Hills Fire Protection District, making firefighter Craig Allen's Detroit-style pizza.
Source: fox32news - 🏆 547. / 51 Read more »
Mika Zibanejad heating up at perfect time as Rangers look to put Capitals' backs to wallThe largest indictment surrounding previous playoff runs by the New York Rangers — which ended all too prematurely by their standards — was that their biggest
Source: amNewYork - 🏆 336. / 59 Read more »
April’s water temps are heating like rocket fuel for stormsRecord water temps are warmer than last year and are hotter earlier where hurricanes form most often in the Atlantic's peak season.
Source: wjxt4 - 🏆 246. / 63 Read more »
Natural Gas looks set to rally as Europe gears up for next heating seasonNatural Gas (XNG/USD) prices are holding ground above $2.00 on Friday after a brief dip earlier this week. Gas prices are quickly recovering as mainland Europe is gearing up for the next heating season, with traders starting to negotiate contracts in
Source: FXStreetNews - 🏆 14. / 72 Read more »
Power Hitting Prospects Heating Up In Minors, Guardians NewsKyle Manzardo, Johnathan Rodriguez, and Jhonkensy Noel are finding their swing as the Cleveland Guardians' major league roster shakes out.
Source: SInow - 🏆 273. / 63 Read more »