Healthy Sleep Linked to Lower Odds for Digestive Diseases

Healthier sleep is associated with lower odds of developing a wide range of gastrointestinal conditions, regardless of genetic susceptibility, new research revealed.Due to the widespread prevalence of sleep issues and a growing burden of digestive diseases globally, researchers investigated the association between sleep quality and digestive disorders in a prospective cohort study of 410,586 people in the UK Biobank.

A healthy sleep was defined as a morning chronotype, 7-8 hours of sleep duration, no self-reported snoring, never or rare insomnia, and a low frequency of daytime sleepiness, for a score of 5/5. The study investigators tracked the development of 16 digestive diseases over a mean period of 13.2 years.Participants with a healthy sleep score had 28% lower odds of developing any digestive disease than those with a sleep score of 0/1.A healthy sleep score was also associated with a 37% reduced odds for metabolic dysfunction-associated steatotic liver disease , 34% reduced chance for dyspepsia , and a 25% lower risk for diverticulosis .

High genetic risk and poor sleep scores were also associated with increased odds of developing digestive diseases."Our findings underscore the potential holistic impact of different sleep behaviors in mitigating the risk of digestive diseases in clinical practice," wrote Shiyi Yu, MD, of Guangdong Provincial People's Hospital, Guangzhou, Guangdong, China, and colleagues.

Irritable Bowel Syndrome (IBS) IBS Sleep Disturbance Abnormal Sleep Pattern Sleep Disorder Somnipathy Sleep Genomics Genomic Medicine Metabolic Syndrome Biliary Disease Gallbladder Disease Nonalcoholic Fatty Liver Disease NAFLD Non-Alcoholic Fatty Liver Disease Non-Alcoholic Fatty Liver Disease (NAFLD) Genetics Insomnia Sleeplessness

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