He Jiankui's research on CRISPR babies dubbed 'delusional and outrageous' as experts see manuscripts for first time

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Research on the birth of twins after genome editing for HIV resistance was sent to MIT Technology Review earlier this year.

after a review into his work concluded he had carried out gene editing despite this practice being"officially banned in the country."

Fyodor Urnov, genome-editing scientist at the University of California, Berkeley, told MIT:"The claim they have reproduced the prevalent CCR5 variant is a blatant misrepresentation of the actual data and can only be described by one term: a deliberate falsehood. The study shows that the research team instead failed to reproduce the prevalent CCR5 variant. The statement that embryo editing will help millions is equal parts delusional and outrageous.

He Jiankui announced the world's first gene-edited babies at a conference in Hong Kong in November 2018. Manuscripts from the research have now been published by MIT Technology Review."The article also does not discuss the Chinese ban on assisted reproductive services for HIV-positive parents," Greely told the magazine."It has been reported that He had other men pretend to be the intended fathers for [the] purpose of the required HIV tests. The article doesn't say this.

"This…proves that the research team placed their interests above those of the couple who donated the embryos and of their prospective children," he told the magazine."It was essential to have determined that [the new genes would be HIV resistant] before the embryos were implanted. They could have done so using a known assay: introduce the same edits into immune system cells in the laboratory and then infect them with HIV.

Source: Tech Daily Report (techdailyreport.net)

 

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