while under siege from Sparta. The Byzantine Empire was substantially weakened by the “Plague of Justinian” starting in 541 CE, with impacts on Constantinople spreading to Rome and increasing their vulnerability to invasion and decline.
Controlling epidemic disease was critical to the Industrial Revolution’s economic growth. And cities were central to that growth, as growing populations provided agglomerations of workforces and businesses and customers. This created large, dense markets, which in turn spurred innovation in products and services, concentration of capital investment, increased division of labor and worker skills, and further economic growth.
One way to gauge the pandemic’s impact comes from how public health experts measure “excess deaths.” That’s an increase in deaths going above the trend line of previous years, due to some major event or change, like a pandemic. That’s a big number, around the total 2021 population of Denver, Colorado. But so far it is only around 0.2% of our population , with deaths concentrated among older people. For comparison’s sake, the killed around 675,000 people in the USA, around 0.64 percent of that era’s smaller population—“a little more than six in every thousand people.”
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