Guillain-Barre syndrome 'more common than expected' with RSV vaccine in older people, CDC reiterates

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Reports of a rare nervous system disorder are “more common than expected” in older U.S. adults who got the new RSV vaccines.

FILE - This electron microscope image provided by the National Institutes of Health shows human respiratory syncytial virus virions, colorized blue, and anti-RSV F protein/gold antibodies, colorized yellow, shedding from the surface of human lung cells. In a report released Thursday, May 30, 2024, the Centers for Disease Control and Prevention said they are continuing to investigate a link between two new RSV vaccines and cases of a rare nervous system disorder in older U.S. adults.

More than 10 million older adults have gotten either Pfizer or GSK single-dose shots since early August to protect against Health officials have estimated about two cases of Guillain-Barre syndrome in every 1 million people who receive the RSV vaccine within three weeks of getting the shot. The new CDC report focused on 28 cases of the syndrome in people who were vaccinated, and all but one developed symptoms within 21 days. That translated to 1.5 cases per million in people who got the GSK RSV vaccine, and five cases per million in recipients of the Pfizer shot.An estimated 3,000 to 6,000 people develop Guillain-Barre syndrome in the U.S. each year — either after being infected by a virus or linked to a vaccination — and it’s more common in older people, according to the CDC.

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