'Game changer': A shot every 2 months works better than a daily pill to prevent HIV, study says

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Thanks to modern medicine, we now have a once-daily pill that can prevent HIV, a virus that interferes with the body's ability to fight infections. Now, a new study finds that a long-acting injectable medication given as a shot every eight weeks is significantly more effective than a HIV prevention

Thanks to modern medicine, we now have a once-daily pill that can prevent HIV, a virus that interferes with the body's ability to fight infections. However, experts say the pill doesn't work for everyone's lifestyle, and it's important for people to have other options so they can better protect themselves from HIV infection.

The study, which comes from the HIV Prevention Trials Network and was published at the 23rd International AIDS Conference, builds on prior research showing the shot was equally effective to the pill. The shot, called cabotegravir, has not yet been FDA approved."This study is important -- it is the first to try something that is not an oral medication for prevention of HIV, it is the first one looking at HIV prevention that is comparing two active drugs," said Dr.

The study enrolled 4,570 cisgender men and transgender women who had sex with men. The research was conducted at sites located in the United States, Argentina, Brazil, Peru, South Africa, Thailand and Vietnam. People were randomized into two groups: one that used injectable cabotegravir for HIV prevention and the other that used the daily pill Truvada.

"The main message is that there is clearly a new option for HIV prevention," del Rio said."Some people prefer to take pills, and they will work -- but if you're someone who cannot take pills every day, maybe reluctant, there is an option now to use an injection."

 

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