Registered pharmacist Sapna Patel demonstrates the preparation of a dose of the monkeypox vaccine at a pop-up vaccination clinic in West Hollywood, Calif. on Aug. 3.The Food and Drug Administration issued an emergency use authorization on Tuesday that allows health care providers to reduce the dose of the monkeypox vaccine to one-fifth of what has been given until now.
"In recent weeks the monkeypox virus has continued to spread at a rate that has made it clear our current vaccine supply will not meet the current demand," FDA Commissioner Robert Califf said."The FDA quickly explored other scientifically appropriate options to facilitate access to the vaccine for all impacted individuals. By increasing the number of available doses, more individuals who want to be vaccinated against monkeypox will now have the opportunity to do so.
"Basically you’re getting more bang for your buck," explained William Moss, executive director of the International Vaccine Access Center at Johns Hopkins Bloomberg School of Public Health. "Is this going to put us in a situation where we have to go back and do additional shots?" said Arthur Caplan, a bioethics professor at NYU Grossman School of Medicine.
"It’s with a single dose that I think there would be more concern about the duration of the immune protection," he said.Rochelle Walensky, director of the Centers for Disease Control and Prevention, estimated last week that there are up to 1.7 million people at the highest risk for contracting monkeypox right now. That's based on the number men who have sex with men who are living with HIV or are eligible for preventative HIV treatment.
Caplan said White House officials"seem to be in a bind because they’re in short supply, but they kind of put themselves in that situation."Moss said the discussion about splitting vaccine doses"is being driven by the supply shortage, not by any sense that this is somehow a superior method of administering a vaccine, although it could be.
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