Facile access to fused 2D/3D rings via intermolecular cascade dearomative [2 + 2] cycloaddition/rearrangement reactions of quinolines with alkenes - Nature Catalysis

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Fig. 5: Substrate scope of [2 + 2] cycloaddition/cyclopropanation with respect to quinolines.

Reaction conditions: quinolines , alkenes , HCl and Ir-F in HFIP were stirred for 16 h under argon and irradiated with 30 W blue LEDs . For experimental details, see Supplementary Methods. Ac, acetyl; d.r., diastereomeric ratio. Orange and green circles denote specific substituted carbon atoms to help visualizing the skeletal modification events.Reaction conditions: quinolines , alkenes , HCl and Ir-F in HFIP were stirred for 48 h under argon and irradiated with 30 W blue LEDs .

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