Revumenib is being developed by the company Syndax. It’s meant to work by inhibiting a protein called menin, which seems to play an important role in certain forms of leukemia. These cancers are characterized by carrying a NPM1 gene mutation or a rearrangement of another gene, called KMT2A.
“For patients with acute leukemia who have undergone several previous treatments, this is a very encouraging result,” said study author Scott Armstrong, president of the Dana-Farber and Boston Children’s Cancer and Blood Disorders Center, in a
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