Drug could help thousands with advanced breast cancer, researchers say

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The latest gain for targeted cancer therapy could open new treatment possibilities to thousands of patients with advanced breast cancer.

Wesley Culver, 17, spoke with FOX Television Stations about how his bout with cancer helped him discover his artistic side.

About half of patients with late-stage breast cancer formerly categorized as HER2-negative may actually be HER2-low and eligible for the drug. The drug was already approved for HER2-positive breast cancer, and in April the Food and Drug Administration granted it breakthrough status for this new group of patients.In the new study, the drug lengthened the time patients lived without their cancer progressing and improved survival compared with patients given standard chemotherapy.

"It’s a practice-changing study," said Dr. Sylvia Adams, who directs breast cancer care at NYU Langone Health and enrolled several patients in the study. "It addresses a major unmet need for patients who have metastatic breast cancer."Now, it will be important to define the HER2 gray area to make sure the right patients receive the treatment and then to monitor them closely, experts said.

 

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