Other conditions, such as familial lipodystrophy syndromes or growth hormone deficiency, may be considered depending on the clinical presentation.
Assessing alcohol use is challenging for multiple reasons. I think it must start in the context of a trusting patient-clinician relationship. Most patients report that they have not discussed alcohol use with their healthcare providers, so it's important to remember to discuss it with your patients. In our review, we emphasize that a modest weight reduction of 3%-5% of body weight may be associated with improved NAFLD in lean persons.
You recommend interval assessments of 6 months to 2 years. Please help a clinician understand whether their patient should have intensive vs less intensive monitoring and how this affects management.
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