Does Botox for Migraines Really Work? We Asked the Experts

Here’s what else you need to know about Botox as a migraine treatment:If you have been diagnosed with migraine, talk to your doctor about all potential treatments, including Botox. “There’s actually a strict definition of ‘chronic migraine,’ and who should receive onabotulinumtoxinA for headaches,” says Chia-Chun Chiang, MD, assistant professor of neurology and headache specialist at.

Botox also may be a better choice for those who can’t take other migraine medications due to potential drug interactions, other underlying health conditions, or side effects caused by oral medicine. For example, topiramate may cause tingling in the fingers, or some people may feel fatigued or lightheaded when on betablockers, says McGarry.

Side effects are minimal but may include neck pain, a worsening of headache the first few days after injection, and temporary eyelid droopiness, which usually goes away after three months. “But if you have side effects, you should communicate with your provider because we can modify the location of the injections the next time,” says Dr. Chiang.

The injections are not sedating, so you can drive yourself home. You also should avoid getting chemical hair treatments, such as hair color, for about a week afterwards. “It’s not that it’s dangerous, but no one has studied the chemical interactions, and we want you to get the most out of the treatment,” says Dr. Riggins. And, finally, because you’re probably wondering: No, it won’t change your appearance. The injections for migraine are a different protocol from those used for wrinkles.

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