target both the original coronavirus strain and the currently circulating omicron subvariants BA.4 and BA.5. Trial data suggests these shots should yield better protection against both infection and transmission, as well as more lasting protection against severe illness, Jha said — unless a new variant emerges that significantly upends vaccine effectiveness.
“For the first time since December of 2020, these vaccines, our vaccines, have caught up with the virus,” Jha said. The CDC recommends that all teenagers and adults get the updated booster shots after at least two months have passed since their last Covid vaccine or previous booster. However, experts aren't yet sure how much the updated boosters will really improve protection. The CDC authorized the reformulated shots based on tests in mice, plus human trial data that looked at a similar vaccine targeting the original omicron strain, BA.1. That data showed that updated boosters produced higher levels of antibodies than the original vaccines — a sign of stronger, more lasting protection.
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