City, who made nine changes for the game, could still secure the title this weekend if second-placed Manchester United lose at Aston Villa on Sunday.
"We have another three chances to be champions, we have to learn from this and carry on," said Guardiola.Saturday's game also offered something of a preview of the Champions League final between the two sides, although both Guardiola and Thomas Tuchel left out key players. Within two minutes they had a chance to double that lead from the penalty spot, but Aguero's soft chip down the middle ended in embarrassment as it was easily saved by Edouard Mendy.
But Tuchel's team went on to grab a late winner with Marcos Alonso's scuffed shot floating past Ederson.
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