published in June found that even though such patients responded well to vaccines, it remained unclear how long their protection might last.from May found varying immune responses among certain cancer patients,"especially patients with blood cancers, what we call hematologic malignancies, who also require highly immunosuppressive drugs," Gounder said.
Organ transplant recipients, too, may need additional doses. They must take medications to suppress their immune systems so their bodies do not reject new organs. Those drugs may also dampen the body's response to vaccines.of 30 organ transplant recipients published in June suggested the need for a third dose. Even though all participants had been fully vaccinated with the Moderna or Pfizer-BioNTech vaccines, the majority ended up with no antibodies to the virus.
A third dose, researchers said, boosted the antibody response somewhat, but more studies are needed to determine which patients might benefit most.Whether an additional dose would ultimately be needed can be analyzed in two ways.
All three manufacturers with authorized Covid-19 vaccines in the U.S. have been investigating the safety and effectiveness of additional doses.to determine whether a third shot of the Moderna vaccine could be given after a person has already been fully immunized with the Pfizer or Johnson & Johnson vaccines.
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