Baby born from three people's DNA in UK first

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Most of the baby's DNA comes from their two parents, with a small percentage from a donor.

However, the UK did not immediately press ahead. TheThe Human Fertilisation and Embryology Authority is saying "less than five" babies have been born as of 20 April 2023. It is not giving precise numbers to prevent the families being identified.have emerged after a Freedom of Information request by the Guardian newspaper.

"News that a small number of babies with donated mitochondria have now been born in the UK is the next step, in what will probably remain a slow and cautious process of assessing and refining mitochondrial donation," said Sarah Norcross, the director of the Progress Educational Trust. There has been no word from the teams in Newcastle so it is still uncertain whether the technique was successful.

Prof Robin Lovell-Badge, from the Francis Crick Research Institute, said: "It will be interesting to know how well the mitochondrial replacement therapy technique worked at a practical level, whether the babies are free of mitochondrial disease, and whether there is any risk of them developing problems later in life."

There is technically a risk of "reversion" where any defective mitochondria that are carried over could gain in number and still result in disease.More on this story

 

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