SAN DIEGO — In published trials, both an IL-17 inhibitor and an IL-23 inhibitor achieved impressive rates of clear or almost clear responses in patients with moderate to severe plaque psoriasis, but late-breaker data presented at the annual American Academy of Dermatology meeting show that these types of responses are sustained for as long as patients have remained on therapy..
Follow-up with a novel oral anti-IL-23 inhibitor JNJ-2113 was only 52 weeks, far shorter. But again, the response for the most effective dose at the end of this period was essentially unchanged from that at 16 weeks. Among those on the highest and most effective test dose of once-daily 100 mg, the PASI 90 at 1 year was 64.3%, a rate that was essentially unchanged from week 16.
Source: Entertainment Trends (entertainmenttrends.net)
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