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Alzheimer's Could Be Caused by Brain Cells That Age Too Fast

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Engineers at the University of California San Diego have used cutting-edge technology to analyze the postmortem brains of 14 donors aged over 59, some of whom died with Alzheimer's disease and some of whom did not.

"The technology has the potential to help us uncover novel molecular mechanisms underlying Alzheimer's pathology, which could pave the way for more targeted therapeutic interventions and improved patient outcomes,"to the chromatin of animal models, impacting an individual's lifespan. But the field of research concerning chromatin and aging is still new and"

"This distinction sheds light on the correlation between the chromatin conformation of a cell and its transcriptomic age, thus extending our understanding from previous observations associating chromatin structural decline with aging to the single-cell level," researchers at USCD

 

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