ADCs for Breast Cancer: Clear Benefits, Manageable Risks

Antibody drug conjugates — a class of targeted medications that combine monoclonal antibodies with cytotoxic payloads — are rapidly changing the treatment landscape for patients with metastatic breast cancer .

"Prophylactic cryotherapy — ice chips or ice water held in the mouth throughout the infusion — was also suggested," she said. "There was one patient who had a grade 5 event, which was characterized by the investigator as grade 3 pneumonitis, with death attributed to disease progression," Jhaveri said. This was subsequently adjudicated to be a grade 5 drug-related death.

Any grade diarrhea was reported in 7.5%, with no grade 3+ diarrhea. Alopecia was reported in 36.4%, of which grade 1 was 21% and grade 2 was 15%. Median overall survival was 35.7 months with trastuzumab deruxtecan vs 25.0 months with the treatment of choice, with the risk for death reduced by 31% with trastuzumab deruxtecan .

Source: Healthcare Press (healthcarepress.net)

Metastatic Breast Carcinoma Metastatic Breast Cancer MBC Mbc Advanced BC Metastatic BC Metastatic Breast Cancer (MBC) MBC - Metastatic Breast Cancer Biologic Therapy Biologics Breast Cancer Malignant Breast Neoplasm Breast Carcinoma Antineoplastic Drug Anti-Cancer Agents Erlotinib Gefitinib Imatinib Rituximab Su11248 Sunitinib Trastuzumab Dentistry

United States Latest News, United States Headlines

Similar News:You can also read news stories similar to this one that we have collected from other news sources.

Mammograms should start at 40, panel says, as breast cancer rates rise in younger womenBreast cancer is still the second-most common cause of cancer death for U.S. women.
Source: mercnews - 🏆 88. / 68 Read more »

Mammogram screening to detect breast cancer should now start at 40, panel saysBreast cancer is the second-most common cause of cancer death for U.S. women.
Source: FOX10Phoenix - 🏆 83. / 68 Read more »

U.S. panel, cancer groups differ on new breast cancer screening guidelinesAn influential panel lowered the recommended screening age to 40, but cancer groups say more regular screening is needed.
Source: axios - 🏆 302. / 63 Read more »

Poorer English Breast Cancer Survivors Face Higher Second Cancer RiskI'm a former correspondent for award-winning health policy publication, the Health Service Journal. My work exposing PPE shortages in hospitals during the pandemic was recognized as 'Excellence in Reporting Coronavirus' by Press Gazette. I've been a journalist for nine years and have also written for Newsweek and Metro.co.uk.
Source: ForbesTech - 🏆 318. / 59 Read more »

Could Aspirin Help Treat Breast Cancer?A new study found that taking aspirin as adjuvant therapy does not improve outcomes for patients with high-risk nonmetastatic breast cancer.
Source: Medscape - 🏆 386. / 55 Read more »

Breast cancer rates rising among Canadian women in their 20s, 30s and 40sRates of breast cancer in women under the age of 50 are rising in Canada according to a study which showed an increase in breast cancer diagnoses among females in their twenties, thirties, and forties.
Source: ScienceDaily - 🏆 452. / 53 Read more »