A year after first COVID-19 vaccine, here's what's next for researchers –\u00a0and what worries them

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A year after first COVID-19 vaccine, here's what's next for researchers – and what worries them.

has developed a vaccine that looks to the immune system almost exactly like SARS-CoV-2 –"really nice-looking protein balls with spikes on the surface, almost like the virus, but it's pure protein, so it's safe," said Jiang Zhu, a company co-founder and structural biologist at The Scripps Research Institute in La Jolla, California.

Covering all the variations between MERS, SARS and SARS-CoV-2 will be tough in a single vaccine, though, Haynes said. "We'll find a solution, a way to develop strategies that will work, I'm confident that's going to happen," he said."Whether that's going to happen in 20 years or in 2 years I'm less certain."The challenge over the next year will be getting more shots in arms – in the U.S. and elsewhere, said Hildreth, who has studied viruses for decades and also sits on a federal advisory panel that reviews vaccines. "They can't just be vials sitting on a shelf.

The U.S. and other wealthy countries also have to do a better job of distributing vaccines around the world, he and others said.

 

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Shigella infection (shigellosis) is an intestinal infection caused by a family of bacteria known as shigella. The main sign of shigella infection is diarrhea, which often is bloody. Shigella is very contagious

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In the future, shots may go away altogether, replaced by nasal sprays and microneedles that go on like Band-Aids. But experts agree the main focus of the next year won't be new technologies, but simply getting vaccines into arms.

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