, researchers from Children’s Hospital Westmead in Sydney compared the newborn blood samples of 67 infants who died to those of 10 who lived, matching for date of birth and gender. They compared three groups: infants who lived, infants who died but not from SIDS, and 26 infants who died of SIDS. In blood samples taken two to three days after birth, the levels of butyrylcholinesterase — an enzyme of the autonomic nervous system — was lower in the SIDS group compared to the infants who lived.
Meg Frizzola, chair of pediatrics at Nemours Children’s Health in Delaware, said that the study is exciting but the response to it should be tempered because it is only a first step. She said that more research will be needed before confirming butyrylcholinesterase as a biomarker, understanding the mechanism, and then — if all that comes to fruition — figuring out what to do with the information to actually prevent infant deaths.
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